
Friday, April 11, 2008
Straits Times Index 3 Black Crows Clone Candlesticks Reversal

The Agile Gene: How Nature Turns on Nurture
Ridley writes that the switches controlling our 30,000 or so genes not only form the structures of our brains but do so in such a way as to cue off the outside environment in a tidy feedback loop of body and behavior. In fact, it seems clear that we have genetic "thermostats" that are turned up and down by environmental factors. He challenges both scientific and folk concepts, from assumptions of what's malleable in a person to sociobiological theories based solely on the "selfish gene."
Ridley's proof is in the pudding for such touchy subjects as monogamy, aggression, and parenting, which we now understand have some genetic controls. Nevertheless, "the more we understand both our genes and our instincts, the less inevitable they seem." A consummate popularizer of science, Ridley once again provides a perfect mix of history, genetics, and sociology for readers hungry to understand the implications of the human genome sequence. --Therese Littleton --This text refers to the Hardcover edition."Nature versus nurture" sums up in a nutshell one of the most contentious debates in science: Are people's qualities determined by their genes (nature) or by their environment (nurture)? The debate has only grown louder since the human genome has been found to comprise only 30,000 genes. Some scientists claim that we don't have enough genes to account for all the existing human variations. Ridley, author of the bestseller Genome, says that not only are nature and nurture not mutually exclusive, but that "genes are designed to take their cue from nurture." Genes are not unchanging little bits of DNA: their expression varies throughout a person's life, often in response to environmental stimuli. Babies are born with genes hard-wired for sight, but if they are also born with cataracts, the genes turn themselves off and the child will never acquire the ability to see properly. On the other hand, stuttering used to be ascribed solely to environmental factors. Then stuttering was found to be clearly linked to the Y chromosome, and evidence for genetic miswiring of areas in the brain that manage language was uncovered. But environment still plays a role: not everyone with the genetic disposition will grow up to be a stutterer. Ridley's survey of what is known about nature-nurture interactions is encyclopedic and conveyed with insight and style. This is not an easy read, but fans of his earlier book and readers looking for a challenging read will find this an engrossing study of what makes us who we are.
http://www.amazon.com/Agile-Gene-Nature-Turns-Nurture/dp/B000GYI1HO/ref=pd_sim_dbs_b_img_2
DNA: The Secret of Life
After 1975, DNA was no longer solely the concern of academics trying to understand the molecular underpinnings of life. The molecule moved beyond the cloisters of white-coated scientists into a very different world populated largely by men in silk ties and sharp suits.In later chapters, Watson aims barbs at those who are concerned by genetic tinkering, calling them "alarmists" who don't understand how the experiments work. It is in these arguments that Watson may lose favor with those whose notions of science were born after Silent Spring. Nevertheless, DNA encompasses both sides of the political issues involved in genetics, and Watson is an enthusiastic proponent of debate on the subject. The book accompanies a 5-part PBS series. --Therese Littleton
Who better than James Watson to lead a guided tour of DNA? When he and his English colleague, Francis Crick, discovered the double helix structure of the DNA molecule in 1953, little could they imagine that a mere 50 years later scientists would be putting the finishing touches on a map of the human genome. In this magisterial work, Watson, who won the Nobel Prize with Crick for their discovery, guides readers through the startling and rapid advances in genetic technology and what these advances will mean for our lives. Watson covers all aspects of the genome, from the layout of four simple bases on the DNA molecule through their complex construction into genes, then to the mechanisms whereby proteins produced by genes create our uniquely human characteristics-as well as the genetic mutations that can cause illnesses or inherited diseases like Duchenne muscular dystrophy and Huntington's disease. Watson may have mellowed a little over the years since he displayed his youthful brashness in The Double Helix, but he still isn't shy about taking on controversial subjects. He criticizes biotech corporations for patenting genes, making diagnostic medical procedures horribly expensive and damping further basic research. He notes that while China and other countries with large populations to feed have eagerly grasped the potential of genetically modified foodstuffs, America squandered $100 million on a recall of taco shells and the genetically modified corn used in them. He pleads passionately for the refinement and widespread use of prenatal genetic testing. Watson will probably provoke the most controversy with his criticism of scientists, corporations and government funding sources for their avoidance of important areas of research-notably the genetics of skin coloration-for political reasons. Every reader who wants to understand their own medical future will want to read this book. 100 color and b&w illus.
http://www.amazon.com/DNA-Secret-James-D-Watson/dp/0375415467/ref=pd_bbs_sr_1?ie=UTF8&s=books&qid=1207918158&sr=1-1
Science Clubs - Questa Club
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http://www.science.edu.sg/ssc/clubs.jsp?type=3&root=0&parent=0&cat=113
Life Sciences Institute Research Programmes
Research Programmes
In collaboration with the five Faculties and Schools (Computing, Dentistry, Engineering, Medicine and Science), LSI has initiated and is overseeing 13 research programmes. These programmes aim to tackle some of the major diseases relevant to Singapore. Several platform technologies are also involved in achieving this aim. About 200 Principal Investigators are currently involved in one or more of these 12 research programmes.
Diseases
Platform Technologies
LSI focuses on enhancing research in these strategic areas within NUS. At the same time, it encourages collaboration with globally renowned institutions here and overseas.
Life Sciences
- Biochemistry
- Chemistry of a specific process or art of living organisms.
- Biomedicine
- Techniques, procedures, and equipment aspects of biology in medicine.
- Biotechnology
- Cell Biology
- The study of cells of organisms.
- Genetics
- The study of heredity and variation in organisms.
- Marine Biology
- The study of organisms in marine and fresh-water environments.
- Microbiology
- The study of microorganisms (microbes).
- Molecular Biology
- The study of the ultimate physiochemical nature of organisms.
- Plant Biology (Botany)
- The study of plant life.
- Zoology
- The study of animal life.
http://www.ipl.org/div/subject/browse/sci36.00.00/
Temasek Life Sciences Laboratory
Temasek Life Sciences Laboratory (TLL) is a non-profit organization established in 2002 to undertake cutting edge research in molecular biology and genetics utilizing a broad range of model organisms. TLL is affiliated to the National University of Singapore and Nanyang Technological University. It is located within the campus of the National University of Singapore and is situated alongside other research institutes and academic departments of the university.
TLL has a current research staff of about 190 scientists. Our vision is to create an environment which can attract the brightest young minds world wide, support their research and challenge them to be leaders in their own fields. The institute is based on small but well supported and interactive research groups in which originality, innovation and creativity are emphasized. Collaboration between research groups within TLL and with other local and international research groups is actively encouraged.
Disproportionate to our small size, TLL has already had a positive impact on the development of biotechnology industry in Singapore through collaborations and joint research ventures with local and international partners. Through the excellence of our research, the talented people we nurture and our collaborations with educational, research, as well as industrial partners we will help to facilitate the development of life sciences based industries in Singapore.